TOPIC:

My SE Flex is exhibiting some strange behavior that I can't figure out how to fix.  If I use the rotary knob to take the Flex out of standby it does not produce any sound unless I power cycle it by unplugging it.  However, it works fine if I use the remote to take it out of standby.  This is consistent and repeatable so not something that just happens intermittently.  Anybody else seen or know how to fix this?  Not a deal breaker if it's a known bug.

I am also having the same problem. I have not tried remote control as you have.
I have tow issues.
First: If AVR LFE takes flex out standby, no outputs from sub until I power cycle it. Same is true if I do it via the knob.
Second: if I change presets it looses the output until I power cycle again. For example, Preset 1 is working after power cycle, now I change to Preset 2, no output from subs. But if I power cycle, preset 2 will start working. 

for $500 equipment that’s not good. I have created support ticket, will see what the resolution comes out of it. First reply to ticket is not good as it says check output 3 & 4, may be I disabled it. But that’s not true as I have four subs. I have a feeling that I will be going thru these kind a support until they start looking at their unit instead of telling me to check my connections and to read manual.

@aaronjs

Odd indeed! Not something we can easily reproduce here.. 

Most likely something odd about a)configuration b)Maybe an outdated firmware? 
Step#1: Make sure you're running Device Console (only software we active support from there on) 
Step#2: Make sure you're running the latest DSP and XMOS versions 
Step#3: When you do get that issue, simply send a snapshot to our team via a support ticket on our portal (support.minidsp.com) .
 

What are current versions? Console shows MCU 1.59 and DSP 1.5 after clicking on refresh DSP and Refresh XMOS